ALTERATIONS OF LACTATE DEHYDROGENASE ACTIVITY IN THE SKELETAL MUSCLES AND CARDIAC TISSUE OF SALMONID AFTER DISINFECTING PROCEDURE WITH CHLORAMINE-T

Chloramine-T is a widely used disinfectant for the treatment of gill diseases fish in freshwater and can be toxic to fish. Therefore, current study aimed examine safety this disinfecting product (as it has been attracting researchers’ attention applying aquatic animals) health using markers aerobic anaerobic capacity (i.e. lactate dehydrogenase activity) skeletal muscle cardiac tissues rainbow trout (Oncorhynchus mykiss Walbaum), grayling (Thymallus thymallus Linck), brown (Salmo trutta m. fario). Twenty-two clinically healthy trout, twenty-one twenty graylings were exposed final concentration 9 mg per L. The Control group was handled same way as groups. Fish bathed 20 min repeated three times every 3 days. Two days after last bathing sampled. In tissue, LDH activity decreased disinfection by compared unhandled controls. On other hand, increased tissue trout. caused decrease grayling. Moreover, controls, higher 107.5% (p = 0.000) 57.6% 0.001) values obtained muscles. present investigation demonstrates alterations muscles procedure with dose Although, disinfection, showed trends responses indicating adaptive response against toxicity. Similar observed increased. these biochemical parameters considered indicators assessment effects, although further studies are required investigating mechanism involved pattern.